ea0028p199 | Obesity, diabetes, metabolism and cardiovascular | SFEBES2012
Forbes Shareen
, Reynolds Rebecca
, Harold Graham
, Howie Forbes
, Denison Fiona
, Norman Jane
Introduction: During gestation diminished maternal insulin sensitivity (IS) increases the availability of fuels allowing fetal growth. Very severe obesity (Class III obesity (OB), BMI≥40 kg/m2) is associated with reduced IS but it is 28 how nutrient availability differs and how this impacts on birth weight versus normal pregnancies (CON). Methods: 213 OB (median (interquartile range) 43.2(41.146.3) kg/m2) and 87 CON (BM...